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Instructions for Breast Cancer Research authors |
General information
Breast Cancer Research is a multidisciplinary journal that publishes research articles of exceptional interest in all areas of biology and medicine relevant to breast cancer. Articles explore the biological basis of breast cancer and the clinical application of this knowledge. Clinical studies will usually be phase I and II clinical trials. The journal also regularly publishes reviews, commentaries and reports on topics related to this research. These are usually commissioned, but suggestions in the form of a brief summary are welcome and should be sent to the Editorial Office. Online submission process To facilitate rapid publication and to minimize administrative costs, Breast Cancer Research prefers online submission. The submission process is compatible with version 3.0 or later of Internet Explorer and Netscape Navigator, and with most other modern web browsers. It can be used from PC, Mac, or Unix platforms. Files can be submitted as a batch, or one by one. The submission process can be interrupted at any time - when users return to the site, they can carry on where they left off. See below for examples of acceptable word processor and graphics file formats. Additional files of any type, such as movies, animations, or original data files, can also be submitted as part of the publication. During submission you will be asked to provide a cover letter. Please use this to explain why your manuscript should be published in the journal and to elaborate on any issues relating to our editorial policies detailed in the instructions for authors. You will also be asked to provide the names and contact details of 2-4 potential reviewers for your manuscript. Assistance with the process of manuscript preparation and submission is available from the editorial office ( editorial@breast-cancer-research.com )
Article-processing charges
Policies Any manuscript , or substantial parts of it, submitted to the journal must not be under consideration by any other journal although it may have been deposited on a preprint server. The manuscript should not have already been published in any journal or other citable form, with the exception that the journal is willing to consider peer-reviewing manuscripts that are translations of articles originally published in another language. In this case, the consent of the journal in which the article was originally published must be obtained and the fact that the article has already been published must be made clear on submission and stated in the abstract. Authors are required to ensure that no material submitted as part of a manuscript infringes existing copyrights, or the rights of a third party. Authors who publish in Breast Cancer Research retain copyright to their work ( more information ). The authors are understood to give Breast Cancer Research permission to reproduce the article or portions of it for print and online distribution; advertisements may be included to help defray the costs of handling and distribution. Correspondence concerning articles published in Breast Cancer Research is encouraged. Correspondence containing data or scientific argument is subject to peer-review. Submission of a manuscript to Breast Cancer Research implies that all authors have read and agreed to its content, that readily replaceable material described in the article will be freely distributed to academic colleagues, and that any experimental research that is reported in the manuscript has been performed with the approval of an appropriate ethics committee. Research carried out on humans must be in compliance with the Helsinki Declaration, and any experimental research on animals must follow internationally recognized guidelines. A statement to this effect must appear in the Methods section of the manuscript, including the name of the body which gave approval, with a reference number where appropriate. Informed consent must also be documented. Manuscripts may be rejected if the editorial office considers that the research has not been carried out within an ethical framework, e.g. if the severity of the experimental procedure is not justified by the value of the knowledge gained. Generic drug names should generally be used. When proprietary brands are used in research, include the brand names in parentheses in the Methods section. We ask authors of Breast Cancer Research papers to complete a declaration of competing interests, which should be provided as a separate section of the manuscript, to follow the Acknowledgements. Where an author gives no competing interests, the listing will read 'The author(s) declare that they have no competing interests'. Much has been written about competing interests (or conflict of interest, as other journals call it) within scientific research, but the following articles provide some background:
R Smith: Making progress with competing interests. BMJ 2002, 325 :1375-1376 CD DeAngelis, PB Fontanarosa, A Flanagin: Reporting financial conflicts of interest and relationships between investigators and research sponsors. JAMA 2001, 286 :89-9 K Morin, H Rakatansky, FA Riddick Jr, LJ Morse, JM O'Bannon 3rd, MS Goldrich, P Ray, M Weiss, RM Sade, MA Spillman: Managing conflicts of interest in the conduct of clinical trials. JAMA 2002, 287 :78-84 For all articles that include information or clinical photographs relating to individual patients, written and signed consent from each patient to publish must also be mailed or faxed to the editorial staff. The manuscript should also include a statement to this effect in the Acknowledgements section, as follows: "Written consent for publication was obtained from the patient or their relative." Breast Cancer Research supports initiatives to improve the performance and reporting of clinical trials, part of which includes prospective registering and numbering of trials. While there are initiatives to ensure that all clinical trials are registered (most notably the recent statement from the International Committee of Medical Journal Editors - see http://www.icmje.org/clin_trialup.htm), we are focussing on controlled trials of healthcare interventions, for now. Authors of protocols or reports of controlled trials of health care interventions must register their trial prior to submission in a suitable publicly accessible registry. The trial registers that currently meet all of the ICMJE guidelines can be found at http://www.icmje.org/faq.pdf. The trial registration number should be included as the last line of the abstract of the manuscript. Breast Cancer Research also supports initiatives aimed at improving the reporting of biomedical research. Checklists have been developed for randomized controlled trials (CONSORT), systematic reviews (QUOROM), meta-analyses of observational studies (MOOSE), diagnostic accuracy studies (STARD) and qualitative studies (RATS). Authors are requested to make use of these when drafting their manuscript and peer reviewers will also be asked to refer to these checklists when evaluating these studies. For authors of systematic reviews, a supplementary file, linked from the Methods section, should reproduce all details concerning the search strategy. For an example of how a search strategy should be presented, see the Cochrane Reviewers' Handbook. Authors from pharmaceutical companies, or other commercial organizations that sponsor clinical trials, should adhere to the Good Publication Practice guidelines for pharmaceutical companies, which are designed to ensure that publications are produced in a responsible and ethical manner. The guidelines also apply to any companies or individuals that work on industry-sponsored publications, such as freelance writers, contract research organizations and communications companies. The involvement of medical writers or anyone else who assisted with the preparation of the manuscript content should be acknowledged, along with their source of funding, as described in the European Medical Writers Association (EMWA) guidelines on the role of medical writers in developing peer-reviewed publications. If medical writers are not listed among the authors, it is important that their role be acknowledged explicitly. We suggest wording such as 'We thank Jane Doe who provided medical writing services on behalf of XYZ Pharmaceuticals Ltd.'. Nucleic acid sequences, protein sequences and atomic coordinates should be deposited in an appropriate database in time for the accession number to be included in the article. Where appropriate, authors should adhere to the standards proposed by the Microarray Gene Expression Data Society (http://www.mged.org) and must deposit microarray data in one of the public repositories, such as ArrayExpress (http://www.ebi.ac.uk/arrayexpress), Gene Expression Omnibus (GEO; http://www.ncbi.nlm.nih.gov/projects/geo/) or the Center for Information Biology Gene Expression Database (CIBEX; http://cibex.nig.ac.jp). Any 'in press' articles cited within the references and necessary for the reviewers' assessment of the manuscript should be made available if requested by the editorial office. BioMed Central is a member of the Committee on Publication Ethics (COPE). Authors who have appealed against a rejection but remain concerned about the editorial process can refer their case to COPE. For more information, visit www.publicationethics.org.uk. BioMed Central endorses the World Association of Medical Editors (WAME) Policy Statement on Geopolitical Intrusion on Editorial Decisions. Immediate publication on acceptance Once an original research article is accepted, it is published in Breast Cancer Research immediately as a provisional PDF file, with a final citation, and will be included in PubMed. The article will subsequently be copyedited and published in both a fully browseable web form and as a formatted PDF; the article will then be available through Breast Cancer Research, BioMed Central and PubMed Central. |
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Preparing main manuscript text
File formats
Users of other word processing packages should save or convert their files to RTF before uploading. Many free tools are available which ease this process. TeX/LaTeX users: We recommend using BioMed Central's TeX template and BibTeX stylefile. If you use this standard format, you can submit your manuscript in TeX format (after you submit your TEX file, you will be prompted to submit your BBL file). If you have used another template for your manuscript, or if you do not wish to use BibTeX, then please submit your manuscript as an RTF file. Publicon users: Information about Publicon and instructions for authoring in Publicon are available. Note that figures must be submitted as separate image files, not as part of the submitted DOC/ TEX file.
Manuscript sections for Research articles
The Accession Numbers of any nucleic acid sequences, protein sequences or atomic coordinates cited in the manuscript should be provided, in square brackets and include the corresponding database name; for example, [EMBL:AB026295, EMBL:AC137000, DDBJ:AE000812, GenBank:U49845, PDB:1BFM, Swiss-Prot:Q96KQ7, PIR:S66116]. The databases for which we can provide direct links are: EMBL Nucleotide Sequence Database (EMBL), DNA Data Bank of Japan (DDBJ ), GenBank at the NCBI (GenBank), Protein Data Bank (PDB), Protein Information Resource (PIR) and the Swiss-Prot Protein Database (Swiss-Prot).
Title page
A versus B in the treatment of C: a randomized controlled trial X is a risk factor for Y: a case control study The full names, institutional addresses, and e-mail addresses for all authors must be included on the title page. The corresponding author should also be indicated.
Abstract
Introduction
Materials and methods
Results and Discussion
Conclusions
List of abbreviations
Competing interests
Authors are required to complete a declaration of competing interests. All competing interests that are declared will be listed at the end of published articles. Where an author gives no competing interests, the listing will read 'The author(s) declare that they have no competing interests'. When completing your declaration, please consider the following questions: Financial competing interests
Non-financial competing interests Are there any non-financial competing interests (political, personal, religious, ideological, academic, intellectual, commercial or any other) to declare in relation to this manuscript? If so, please specify. If you are unsure as to whether you, or one your co-authors, has a competing interest please discuss it with the editorial office.
Authors' contributions
An "author" is generally considered to be someone who has made substantive intellectual contributions to a published study. To qualify as an author one should 1) have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; 2) have been involved in drafting the manuscript or revising it critically for important intellectual content; and 3) have given final approval of the version to be published. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content. Acquisition of funding, collection of data, or general supervision of the research group, alone, does not justify authorship. We suggest the following kind of format (please use initials to refer to each author's contribution): AB carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript. JY carried out the immunoassays. MT participated in the sequence alignment. ES participated in the design of the study and performed the statistical analysis. FG conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript. All contributors who do not meet the criteria for authorship should be listed in an acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general support.
Acknowledgements
The role of a medical writer must be included in the acknowledgements section, including their source(s) of funding. Authors should obtain permission to acknowledge from all those mentioned in the Acknowledgements. Please list the source(s) of funding for the study, for each author, and for the manuscript preparation in the acknowledgements section. Authors must describe the role of the funding body, if any, in study design; in the collection, analysis, and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication.
References
Only articles and abstracts that have been published or are in press, or are available through public e-print/preprint servers, may be cited; unpublished abstracts, unpublished data and personal communications should not be included in the reference list, but may be included in the text. Notes/footnotes are not allowed. Obtaining permission to quote personal communications and unpublished data from the cited author(s) is the responsibility of the author. Journal abbreviations follow Index Medicus/MEDLINE. For each reference, name all authors unless there are more than ten, in which case name the first ten followed by et al. We encourage authors to use a recent version of EndNote (version 5 and above) or Reference Manager (version 10) when formatting their reference list, as this allows references to be automatically extracted. Authors submitting articles in EndNote 5 or higher or Reference Manager 10 format will save £30 on the £950 (€1265, US$1860) article processing charge. In order to obtain this discount, you should upload the manuscript file containing your EndNote or Reference Manager-formatted bibliography as a .doc file. Please ensure you do not convert to another format (e.g. RTF or PDF). On upload, the discount will be automatically granted and you will receive a confirmation on-screen and by email. You will also be able to preview an HTML version of the extracted references during submission, and we urge authors to check this. EndNote or Reference Manager users should also make sure that any changes made to the reference list are done within their reference management program, rather than by manually editing the formatted bibliography. This is because manually introduced changes will not be picked up in the automatically extracted list. Further details about EndNote and Reference Manager are available on the BioMed Central site, including style files that conform to the BioMed Central style and information about how to upgrade. Users of other reference management programs should be able to select other journal styles that output a numeric list styled similarly to the guide below. For EndNote users, we provide a detailed technical guide to help with resolving problems that are encountered with the automated reference extraction process. Please check that your reference extraction is accurate after uploading the manuscript text file. We are also working towards integrating data from RefWorks referencing software. We are working in partnership with the development team of RefWorks to produce a high quality extraction process. Examples of the Breast Cancer Research reference style are shown below. Please take care to follow the reference style precisely; references not in the correct style may be retyped, necessitating tedious proofreading.
Links
Breast Cancer Research reference style
Article within a journal
Article within a journal supplement
In press article
Published abstract
Article within conference proceedings
Book chapter, or article within a book
Whole issue of journal
Whole conference proceedings
Complete book
Monograph or book in a series
Book with institutional author
PhD thesis
Link / URL
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Preparing illustrations and figuresFigures should be provided as separate files . Each figure should comprise only a single file. There is no charge for the use of color. Please read our figure preparation guidelines for detailed instructions on maximising the quality of your figures , for further information please contact the Editorial Office .
Formats
Breast Cancer Research will edit all figures supplied by the author. For this reason it is especially important that authors should supply figures in vector form, to facilitate such editing.
Figure
legends
Please note that it is the responsibility of the author(s) to obtain permission from the copyright holder to reproduce figures or tables that have previously been published elsewhere. |
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Preparing tablesEach table should be numbered in sequence using Arabic numerals (i.e. Table 1, 2, 3 etc.). Tables should also have a title that summarizes the whole table, maximum 15 words. Detailed legends may then follow, but should be concise. Tables integral to the manuscript can be pasted into the end of the document text file, in portrait format (note that tables on a landscape page must be reformatted onto a portrait page or submitted as additional files). These will be typeset and displayed in the final published form of the article. Such tables should be formatted using the 'Table object' in a word processing program to ensure that columns of data are kept aligned when the file is sent electronically for review; this will not always be the case if columns are generated by simply using tabs to separate text. Commas should not be used to indicate numerical values. Color and shading should not be used. Larger datasets can be uploaded separately as additional files. Additional files will not be displayed in the final, published form of the article, but a link will be provided to the files as supplied by the author. Tabular data provided as additional files can be uploaded as an Excel spreadsheet (.xls) or comma separated values (.csv). As with all files, please use the standard file extensions. |
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Preparing additional files
Web-only material
Additional files
Additional data files may be referenced generically within the body of the article. e.g. "See additional data file 1 for the original data used to perform this analysis". Additional files are considered integral to articles published by Breast Cancer Research. There is no distinction between the main article and 'supplementary material'. Files will be virus-scanned on submission.
File formats
File extensions
Mini-websites
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Proofs and reprintsProofs will be sent by email. Corrections should be returned within 2 days, preferably by fax or courier if sending paper proofs. Please provide a typed list of corrections clearly indicating where the corrections should be made and please send this list by e-mail. Any substantial additions must be in the form of a note added in proof. Reprints may be purchased for articles published. Prices are available from the Editorial Office. |
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Style and language
General
Gene names should be in italic, but protein products should be in plain type.
There is no explicit limit on the length of articles submitted, but authors are encouraged to be concise. There is no restriction on the number of figures, tables or additional files that can be included with each article online.
Authors should include all relevant supporting data with each article.
Help and advice on scientific writing
Abbreviations
Units
Last revised: 3 October 2005 |
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